Zn ^(2+) Release Performance in Simulated Uterine Solution and Surface Characteristics of ZnO/LDPE Nanocomposites  

作　　者：杨志红 

机构地区：[1]State Key Laboratory of Plastic Forming Simulation and Mould Technology, Department of Material Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China, Faculty of material science and chemical engineering, China University of geosciences, Wuhan 430074, China

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2005年第B12期44-47,共4页武汉理工大学学报（材料科学英文版）

基　　金：FundedbytheNationalNaturalScienceFoundationofChina(No.50271029and50041024),theTenfifthProjectofMinistryofScienceandTechnology(No.2004BA709B1401),theNaturalScienceFoundationofChinaUniversityofGeosciences(No.CUGQNL0521)

摘　　要：Zinc oxide/low-density polyethylene （LDPE） nanocomposites were prepared for intrauterine devices. The change of Zn^2＋ release rates of nanocomposites （ doped with various mass fractions of zinc oxide nanoparticles between 5wt% and 65 wt% ） for 264 days in a simulated uterine solution were investigated. The resuits show that initial burst phases are followed by near zero-order release phases. SEM technique was employed to observe the surface morphology of the 45wt% ZnO/ LDPE composite. Elements and phases on the surface of the nanocomposite after incubation were also analyzed by EDX and XRD respectively. The experimental results show that incrustation formation does not occur after incubation.Zinc oxide/low-density polyethylene （LDPE） nanocomposites were prepared for intrauterine devices. The change of Zn^2＋ release rates of nanocomposites （ doped with various mass fractions of zinc oxide nanoparticles between 5wt% and 65 wt% ） for 264 days in a simulated uterine solution were investigated. The resuits show that initial burst phases are followed by near zero-order release phases. SEM technique was employed to observe the surface morphology of the 45wt% ZnO/ LDPE composite. Elements and phases on the surface of the nanocomposite after incubation were also analyzed by EDX and XRD respectively. The experimental results show that incrustation formation does not occur after incubation.

关 键 词：IUDs ZnO / LDPE nanocomposite Zn^2＋ release rate incrustation formation 

分 类 号：TB383.1[一般工业技术—材料科学与工程]