Composition and Structure of Fibrous Hydroxyapatite Growth on an Injectale Bone Tissue Engineering Scaffolds Material  

作　　者：邱进俊 刘承美 

机构地区：[1]Department of Chemistry, Huazhong Universty of Science and Technology, Wuhan 430074, China

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2005年第B12期159-162,共4页武汉理工大学学报（材料科学英文版）

摘　　要：Fibrous hydroxyapatite （ HA ） wns grown upwards from the crosslinked unsaturated polyphosphoester（ UPPE ） which was used us an injectable bone tissue engineering scaffolds. Composition of fibrous HA was determined by FT- IR, XRD and EDX, which suggested that the fibrous HA was calcium deficient carbonated apatitie with low crystallinity. SEM micrographs indicated that the fibrous HA had a hollow tubing structure and tube wall wus a flakelike assembly. The fibre with poor mechanical property arm with a growth rate about 0. 5 mm/min reached several centimeters in length after 2 hours. The growth was at the tip of the fibre suggested that the procedure of forming fibrous HA was as follows ： Co^2＋ ions were firstly incorporated into the crosslinked UPPE by dipping in Ca^2＋ solution, then supplied through micropores of the material reacted with PO4^3- ions to form α small tuhe , the osmotic pressure or capillary force lead the Ca^2＋ continuously gushed oat into the PO4^3- solution, thus fibrous HA was obtained.Fibrous hydroxyapatite （ HA ） wns grown upwards from the crosslinked unsaturated polyphosphoester（ UPPE ） which was used us an injectable bone tissue engineering scaffolds. Composition of fibrous HA was determined by FT- IR, XRD and EDX, which suggested that the fibrous HA was calcium deficient carbonated apatitie with low crystallinity. SEM micrographs indicated that the fibrous HA had a hollow tubing structure and tube wall wus a flakelike assembly. The fibre with poor mechanical property arm with a growth rate about 0. 5 mm/min reached several centimeters in length after 2 hours. The growth was at the tip of the fibre suggested that the procedure of forming fibrous HA was as follows ： Co^2＋ ions were firstly incorporated into the crosslinked UPPE by dipping in Ca^2＋ solution, then supplied through micropores of the material reacted with PO4^3- ions to form α small tuhe , the osmotic pressure or capillary force lead the Ca^2＋ continuously gushed oat into the PO4^3- solution, thus fibrous HA was obtained.

关 键 词：fibrous hydroxyapatite unsaturated polyphosphoester BONE tissue engineering 

分 类 号：R318.08[医药卫生—生物医学工程]