Synthesis and Characterization of Poly(L-lactide-co-ε-caprolactone) Copolymers  

作　　者：鲁玺丽 蔡伟 

机构地区：[1]School of Materials Science and Engineering, Harbin Institute of Technology,Harbin 150001, China

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2005年第B12期287-289,共3页武汉理工大学学报（材料科学英文版）

基　　金：FundedbytheNationalNaturalScienceFoundationofHelongjiangProvince(No.ZJG0502)

摘　　要：A series of random and block poly（ L-lactide-co-e-caprolactone ） （ PCLA ） copolymers whh different composition are prepared using stannous octaoate as catalyst.The effects of the amount of initiator on the intrinsic viscosity have been investigated. The structure of the PCLA copolymers is characterized by means of nuclear magnetic resonance（ NMR ）, Fourier transform infrared spectrum （ FTIR ）, differential scanning calorimetry （ DSC ） and X- ray diffraction （ XRD ） methods. It is shown that the synthesis condition and the composition of copolymers obrious influence on the structure of PCLA copolymers. Hydrolytic degradation of the copolymers in a PBS solution of pH 7.4 at 37.0℃ shows that the copolymers of different composhions degrade at different rates.A series of random and block poly（ L-lactide-co-e-caprolactone ） （ PCLA ） copolymers whh different composition are prepared using stannous octaoate as catalyst.The effects of the amount of initiator on the intrinsic viscosity have been investigated. The structure of the PCLA copolymers is characterized by means of nuclear magnetic resonance（ NMR ）, Fourier transform infrared spectrum （ FTIR ）, differential scanning calorimetry （ DSC ） and X- ray diffraction （ XRD ） methods. It is shown that the synthesis condition and the composition of copolymers obrious influence on the structure of PCLA copolymers. Hydrolytic degradation of the copolymers in a PBS solution of pH 7.4 at 37.0℃ shows that the copolymers of different composhions degrade at different rates.

关 键 词：L-LACTIDE Ε-CAPROLACTONE random copolymer block copolymer BIODEGRADABILITY 

分 类 号：O631.3[理学—高分子化学]