血管应变显像软件的研制及应用的初步研究  

Design and Application of Vascular Strain Imaging Software via Intravascular Ultrasound

作　　者：张梅[1] 陈良[1] 张鹏飞[1] 易新 苏海军[3] 李晓楠[1] 张运[1] 

机构地区：[1]山东大学医学院,齐鲁医院,教育部和卫生部心血管重构与功能研究重点实验室,济南市250012 [2]北京集翔多维信息技术有限公司 [3]山东大学数学院

出　　处：《中国超声医学杂志》2006年第5期327-329,共3页Chinese Journal of Ultrasound in Medicine

基　　金：国家自然科学基金资助(No.60271015;1030201660402023);卫生部临床学科重点项目(No.20044681);山东省卫生系统高层次人才1020工程(No.2003-17)

摘　　要：目的探讨评价血管及斑块应变的新方法。方法根据理论分析,自行设计了血管应变显像的软件程序。在兔动脉粥样硬化的模型中,进行了腹主动脉血管内超声检查,应用软件程序分析腹主动脉的应变分布。结果应用软件程序可自动识别血管内膜及外膜的边界,血管及斑块的应变值大小可以彩色编码显示,并显示应变的三维分布,脂质型斑块应变值大于纤维型斑块(P<0.05)。结论应用计算机应变软件程序可用于显示血管及斑块的应变分布,为进一步研究斑块的弹性提供了新方法。Objective To investigate a new method for evaluating vascular plaque strains. Methods The abdominal arteries of atherosclerotic rabbits were examined by intravascular ultrasound. The software of vascular strain imaging （VSI） was designed and applied for the analysis of abdominal atherosclerosis strain. Results VSI software might automatically detect the artery intimal and adeventitia border. The local strain could be color-coded and overlapped on the raw ultrasound images and desplayed in three-dimensional strain imaging. The strains of fatty plaques were larger than that of fiberous plaques （P〈0.05） . Conclusions VSI software may provide a reliable method for the measurement of vascular strain, and has the potential value in the diagnosis of plaque elasticity.

关 键 词：软件 应变 动脉粥样硬化 超声 

分 类 号：TP311.52[自动化与计算机技术—计算机软件与理论]