纤维蛋白加凝血酶治疗难治性气胸效果分析  

Analysis of the treatment of 41 refractory pneumothorax cases

作　　者：刘开怀[1] 陈妙爱[1] 侯一峰[1] 

机构地区：[1]汕头大学医学院第二附属医院,广东汕头515041

出　　处：《中国热带医学》2006年第5期834-835,共2页China Tropical Medicine

摘　　要：目的观察纤维蛋白加凝血酶和高渗葡萄糖加庆大霉素在难治性气胸中的治疗效果。方法将41例难治性气胸患者随机分为纤维蛋白加凝血酶治疗组（纤维蛋白组）和高渗葡萄糖加庆大霉素治疗组（高渗葡萄糖组）。在尽可能排除患者胸腔内气体的情况下，分别注入纤维蛋白1．0＋凝血酶200U或50％葡萄糖40ml＋庆大霉素16万U并嘱患者转动体位2-3次。结果纤维蛋白组中获得满意疗效和胸痛较轻的例数均明显高于高渗葡萄糖组（P〈0．05）。结论纤维蛋白加凝血酶对治疗难治性气胸是一种安全，有效的方法。Objective To observe effect of fibrin plus thrombin in combination with 50% glucose and gentamycin on refractory pneumothorax. Methods 41 patients with refractory pneumothorax were randomly divided into two groups and treated with fibrin plus thrombin（ fibrin group）or 50% glucose plus gentamycin （glucose group） respectively, After the air in the thorax was eliminated as less as possible, 1.0 fibrin plus 200U of thrombin or 50 % glucose plus 160,000Uu of gentamycin were injected into the thorax and the patients＇ posture were changed 2 to 3 times, Results The theraeutic effects in the fibrin group were significantly higher than that in the glucose group （ P 〈 0.05）. Conclusion Fibrin plus thrombin is safe and effective for treatment of patients with refractory pneumothorax.

关 键 词：难治性气胸 纤维蛋白 凝血酶 疗效 

分 类 号：R561.4[医药卫生—呼吸系统]