山东省医院感染监控网阴沟肠杆菌耐药性分析  

Antimicrobial Resistance of Enterobacter cloacae:A Study from Shandong Provincial Nosocomial Infection Surveillance System

作　　者：王一兵[1] 李卫光[1] 朱其凤[1] 申翠华[1] 

机构地区：[1]山东省立医院,山东济南250021

出　　处：《中华医院感染学杂志》2006年第5期566-568,共3页Chinese Journal of Nosocomiology

摘　　要：目的 了解阴沟肠杆菌对临床常用抗菌药物的耐药性变化趋势.方法 统计分析山东省医院感染监控网2001年8月～2004年7月,医院感染病例阴沟肠杆菌的耐药情况.结果 山东省医院感染监控网2001年8月～2004年7月共分离到阴沟肠杆菌231株,主要分布于下呼吸道、手术切口、泌尿道等,分别占55.41%、10.82%和9.96%;阴沟肠杆菌对临床常用抗菌药物的耐药率,除亚胺培南外,均有不同程度的增加.结论 阴沟肠杆菌的耐药问题是抗感染治疗的主要威胁,合理使用抗菌药物和采取有效控制措施是避免医院感染暴发流行的重要措施之一.OBJECTIVE To investigate the trends of susceptibility of Enterobacter cloacae isolates to antimicrobial agents from Shandong provincial nosocomial infection surveillance system. METHODS The data from Shandong provincial nosocomial infection surveillance system from Aug 2001 to Jul 2004 were summarized and analyzed. RESULTS In the period of study from Aug 2002 to Jul 2004, 231 strains of E. cloacae were collected, The sputum, urine and wounds were major specimens, and accounted for 55.41%, 10. 82% and 9.96% from total specimens, respectively. The resistant rates of E. cloacae isolates to antimicrobials, except imipenem, increased to some extend. CONCLUSIONS Antimicrobial resistance of clinical isolates of E. cloacae threatens the success of infectious disease treatment. It is very important to promote the rational use of antimicrobial agents for control of resistance and to take effective measures for the prevention of infections.

关 键 词：阴沟肠杆菌 耐药性 

分 类 号：R378.2[医药卫生—病原生物学]