再生障碍性贫血病人院内感染分析  

AN ANALYSIS OF NOSOCOMIAL INFECTION IN PATIENTS WITH APLASTIC ANEMIA

作　　者：李广伦[1] 秦萍[1] 

机构地区：[1]青岛大学医学院附属医院血液内科,山东青岛266003

出　　处：《齐鲁医学杂志》2006年第2期126-127,共2页Medical Journal of Qilu

摘　　要：目的探讨再生障碍性贫血病人院内感染易感因素及预防措施.方法对我院1994年1月～2003年12月再生障碍性贫血病人发生院内感染情况进行回顾性分析.结果再生障碍性贫血病人院内感染率为37%,重型再生障碍性贫血病人为68%;感染好发部位为呼吸道（62%）,其次是血液、口腔等;病原菌以细菌、真菌多见;白细胞计数＜1.0×109/L的病人院内感染率明显高于白细胞计数＞1.0×109/L者（χ2=4.89, P〈0.05）,住院时间＜30 d的病人院内感染率明显低于＞30 d的病人（χ2＝8.35,P＜0.01）.结论再生障碍性贫血病人易发生院内感染.感染最常见部位为呼吸道,住院时间过长、白细胞数过低易增加感染机会.应加强预防措施,尽量减少院内感染,提高病人生存率.Objective To investigate the predisposing factors and the preventive measures of nosocomial infection in pa tients with aplastie anemia（AA）. Methods The data of nosoeomial infection of AA patients admitted during Jan. 1993 to Dec. 2003 were reviewed retrospectively. Results The infection rate in AA was 37% for common cases, and 68% for severe ones. The commonly seen infected parts were respiratory tract （62%）, then was blood, oral cavity, and so on. The usually found pathogens were bacteria （5/8） and fungus （3/8）. The infection in AA with WBC below 1.0 × 10^9/L was higher than those with WBC more than 1.0× 10^9/L （x^2=4.89, P〈0. 05）. Patients with long-term （〉30 d） hospitalization were more easily subjected to the infection （x^2= 8.35, P〈0.0 l）. Conclusion AA patients are more likely to suffer nosocomial infection. Respiratory tract is the most commonly involved. Longer hospital stay, lower WBC, both increase the infection. To improve the survival rate, it is important to strengthen preventive measures of the infection.

关 键 词：贫血 再生障碍性 交叉感染 数据收集 

分 类 号：R551[医药卫生—血液循环系统疾病]