脑泰通颗粒对致痫大鼠机体状态及血液流变学的影响  

Effect of Naotaitong Granule on Organism State and Blood Rheology of Epilepsy Rats

作　　者：白海侠[1] 李军[1] 

机构地区：[1]陕西中医学院,陕西咸阳712046

出　　处：《河南中医》2006年第5期26-27,共2页Henan Traditional Chinese Medicine

摘　　要：目的研究脑泰通颗粒对癫痫大鼠痫性发作程度影响的可能机制及其量效关系。方法通过腹腔注射青霉素建立大鼠急性全身性癫痫发作模型,观察大鼠机体状态的变化,然后取血,测定血液流变学的含量。结果脑泰通颗粒可以改善模型大鼠机体状态,改善血液流变学,与模型组比较有显著性差异(P<0.01或P<0.05)。结论脑泰通颗粒具有改善模型大鼠机体状态的功能,能够降低血液粘度,改善脑部循环,这些可能是脑泰通颗粒治疗癫痫的作用机理。Objective：To study the possible mechanism and its quantity-effect relation of Naotaitong Granule＇s effect on the attack degree of epilepsy rats.Methods：The acute epilepsy attack model were made through the abdominal cavity injection of penicllin to observe.Then the blcod was taken to examine the blcod rheology content.Reaults：Naotaitong Granule could improve the rats＇ organism state and blcod rheology.There was a significant difference in comparison with the model group（P〈0.01 or P〈0.05）.Conclusion：Naotaitiong Granule can improve the orgamism state of the model rats,reduce the bocod viscosity,improve the brain circulation,which are the possible action mechanism of Naotaitong Granule for epilepsy.

关 键 词：癫痫 脑泰通颗粒 大鼠 血液流变学 

分 类 号：R277.721[医药卫生—中医学] R285.5