不同术式子宫切除与性激素及血脂改变的相关性  

RELATIONSHIP BETWEEN DIFFERENT HYSTERECTOMY PROCEDURS AND THEIR CHANGES OF HORMONES AND LIPIDS

作　　者：袁文娟[1] 李金荣[2] 孙航 张炜 郭继梅 王爱梅 

机构地区：[1]青岛市市立医院妇科,山东青岛266071 [2]青岛海慈医疗集团妇产科 [3]青岛市第九人民医院妇产科

出　　处：《青岛大学医学院学报》2006年第2期142-144,共3页Acta Academiae Medicinae Qingdao Universitatis

基　　金：济南铁路局科研基金资助项目(02Y43-6)

摘　　要：目的探讨子宫三角切除术或宫体三角并宫颈筋膜内切除术的临床应用价值.方法子宫良性病变病人115例,根据术中情况及病人意愿分成两组.研究组65例,行新式子宫切除术：切除子宫病变部分,不切断子宫动静脉血管,成形新的“小子宫”,维持原有的卵巢血供和盆腔结构;对照组50例,行筋膜内子宫切除术.观察并比较每组病人术后的临床症状,术前术后性激素、血脂改变情况.结果研究组97%的病人手术前后体内性激素及血脂无明显变化,93%的病人无卵巢功能减退症状,病人术后感觉良好;对照组58%的病人于术后1周～2年内有不同程度的卵巢功能减退症状,术后2年内38%的病人出现性激素、14%的病人出现血脂异常.两组比较,差异有显著性（χ^2=4.67～37.12,P＜0.05）.结论新式子宫切除术能维持原有卵巢功能及盆腔正常解剖结构,使病人的损伤降到了最低程度.Objective To investigate the clinical value of partial triangular hysterectomy. Methods Patients with benigh lesions of uterus, 115 cases, were divided into experimental group （65 cases）： underwent a new style partial hysterectomy, the uterine vessels were completed reserved, a new ＂small uterus＂ rebuilt, without destroying pelvic structure or interrupting the ovarian blood supply; for the control group （50） ,a traditional hysterectomy was done. The changes in levels of hormones and lipids were compared before and after both procedures. Results In the experimental group, 63 patients （970%） had no changes in the levels of hormones or lipids after the surgery, and 60 （93%） had no decrease in ovarian function. However, in the control group, 29 patients （59%） showed a decrease in ovary function from one week up to two years after the surgery, In addition, two years after the operation, 19 patients still had abnormal hormone levels and seven had abnormal lipid level. Significant difference existed between the two groups （X^2 =4.67-37.12,P〈0.05）. Conclusion The new style hysterectomy keeps ovarian function normal and pelvic structures intact, which minimizes damage of the patients.

关 键 词：子宫切除术 性激素类 血脂 

分 类 号：R713.42[医药卫生—妇产科学]