生物节律测控和分析系统的研制及应用  

Design and Application of Biological Rhythm Automatic Monitor and Data Analysis System

作　　者：杨波[1] 刘延友[1] 李颖[1] 廖玍[1] 王晓佳[1] 王正荣[1] 

机构地区：[1]四川大学华西基础医学与法医学院生物医学工程研究室,成都610041

出　　处：《四川大学学报（医学版）》2006年第3期477-479,共3页Journal of Sichuan University(Medical Sciences)

基　　金：国家自然科学基金(批准号30070278;30470623)资助

摘　　要：目的设计研制生物节律测控及分析系统,并以该系统为技术平台研究外环境的改变对动物的生物节律的影响。方法生物节律测控及分析系统采用分布式控制方案,由测控计算机和授时因子发生仪组成。动物活动性检测部分及授时因子发生部分采用模块化设计,根据实验不同要求进行配置。并且通过对饲养在不同的光暗循环周期的小鼠进行生物节律的研究来检测系统的性能及动物对工作平台的适应性。结果该系统选配光线授时因子模块后,显示系统按设计要求完成数据采集及通信、光线调控、数据处理分析。在使用期间没有发生故障。结论系统功能完善,扩展性好,动物适应性好,操作简单,可靠性高,为时间生物学的研究工作提供了可靠的研究平台。Objective To design and develop a biological rhythm monitor and data analysis system for studying biological rhythm in animals under different conditions. Methods The system was a distributed digital control system consisting of a computer and zeitgeber generators. Acquisition of data on animal activity and generation of zeitgeber were modularized to meet the multiple requirements of experiment. System functions and animal adaptability to this system were detected by monitoring the rhythm of mouse activities under different lightdark cycles. Result The animal experiment showed that the functions of this system, including data acquisition, data communication, tight regulation and data analysis, were qualified for application. There was no apparent malfunction. Conclusion The system is safe, reliable and easy to operate. The system could be a very useful system to study biological rhythm in animals.

关 键 词：生物节律 测控系统 授时因子 时间生物学 

分 类 号：TH79[机械工程—仪器科学与技术]