经颅多普勒超声STI、rCBFLI与^(99m)Tc-ECD SPECT脑灌注成像半定量分析比较与应用研究  

Comparisons of STI, rCBFLI by transcranial Doppler and cerebral blood perfusion imaging with ^(99m)Tc-ECD SPECT via semiquantitative analysis

作　　者：吴钢[1] 缪蔚冰[2] 陆兵勋[3] 魏慧星[1] 林军[2] 郑依勇[1] 

机构地区：[1]福建医科大学附属第一医院神经内科,福州350005 [2]福建医科大学附属第一医院核医学科,福州350005 [3]南方医科大学南方医院神经内科,广州510515

出　　处：《中华神经医学杂志》2006年第5期486-489,共4页Chinese Journal of Neuromedicine

基　　金：福建省科技计划重点项目(2003Y038)

摘　　要：目的为阐述经颅多普勒超声(TCD)的狭窄指数(STI)与局部脑血流量丧失指数(rCBFLI) 公式数理逻辑推导的合理性、实用性。方法将TCD检测的脑梗死病例中18例27条颅内动脉狭窄区的STI、rCBFLI指数与相对应区的SPECT脑血流量下降的半定量分析资料进行回顾性对比研究。结果 18例27条颅内动脉狭窄后局部脑血流量下降TCD的rCBFLI值与SPECT相对脑血流量下降值的比较呈线性模型曲线拟合,r=0．62,P<0．001,n=27;局部脑血流量下降的SPECT测量值与TCD的STI值相关曲线拟合呈复合模型曲线拟合,r=0．65,P<0．001,n=27。结论 TCD的STI 和rCBFLI计算公式可以作为评估颅内动脉狭窄程度的新指标。Objective To evaluate the rationality and utility of the formulas of STI and rCBFLI by transcranial Doppler （TCD） which were deduced by mathematical logic. Methods The indexes of TCD＇s STI and rCBFLI of 27 intracranial artery stenosis areas in 18 cerebral infarction patients and the semiquantitative data of the decreased regional cerebral blood perfusion imaging in ^99mTc-ECD SPECT at the corresponding areas were analyzed retrospectively. Results In 27 intracranial artery stenosis areas in the 18 cerebral infarction patients, the decreased values of TCD＇s rCBFLI and the decreased SPECT values by regional cerebral blood perfusion imaging at the corresponding areas presented curve fitting of linear mode, r=0.62, P〈0.001, n=27, while the decreased values of TCD＇s STI and the decreased SPECT values at regional cerebral blood perfusion presented curve fitting of complex mode, r=0.65, P〈0.001, n=27. Conclusion The formulas of STI and rCBFLI of TCD man be viewed as new indexes to evaluate the degree of intracalvarium arterial stenosis.

关 键 词：脑梗死 SPECT 超声检查 多普勒 经颅 

分 类 号：R445[医药卫生—影像医学与核医学]