水泡性口炎病毒感染BHK-21细胞的超微结构改变  

Ultrastructural Changes of BHK-21 Cell Inoculated with Vesicular Stomatitis Virus

作　　者：褚秀玲[1,2] 宋德光[1] 苏建青[3] 韦旭斌[1] 高丰[1] 

机构地区：[1]吉林大学畜牧兽医学院 [2]河北北方学院动物医学系,河北张家口0751312 [3]河北北方学院动物医学系

出　　处：《中国兽医学报》2006年第3期265-267,共3页Chinese Journal of Veterinary Science

基　　金：国家自然科学基金资助项目(30270994)

摘　　要：应用超薄切片技术对水泡性口炎病毒(VSV)在BHK-21细胞上的形态发生和早期发育进行了观察。结果表明,VSV能导致BHK-21细胞圆缩,胞浆严重空泡化,线粒体嵴断裂及空泡化;病毒在细胞浆内复制、增殖,在细胞膜上以出芽方式获得囊膜而成熟。The morphopoiesis and progenesis of the vesicular stomatitis virus in baby hamster kidney celI-21（BHK-21） were observed by using electron microscope. The results showed that BHK-21 cell became round in shape; a lot of vacuoles occurred in its cytoplasm; the mitochondria vacuolated and the ridge of mitochondria ruptured. Virus replicated and then multiplied within the cytoplasm. It was matured through obtaining the capsid from cellular membrane via budding.

关 键 词：水泡性口炎病毒 BHK-21细胞 细胞病变 超微结构 

分 类 号：S851.3[农业科学—预防兽医学]