老龄引起骨质疏松的模拟  

Simulation of Osteoporosis Due to Agedness

作　　者：马宗民[1] 李淑娴[2] 朱兴华[3] 

机构地区：[1]大连大学生物医学工程研究所,大连116021 [2]中国科学院长春光学精密机械与物理研究所应用光学国家重点实验室,长春130031 [3]吉林大学工程力学系,长春130025

出　　处：《生物医学工程研究》2006年第1期14-19,共6页Journal Of Biomedical Engineering Research

基　　金：国家自然科学基金资助项目(10372034)

摘　　要：研究老龄对骨质疏松的影响。应用带有力学调控系统的各向异性骨再造模型结合有限元法进行数值模拟。结果表明进入老年期后,由于肌肉力量的降低和活动量的减少而导致外载荷下降,骨量相对于峰值丢失25%以上,产生骨质疏松。力学因素可导致老年性骨质疏松,表明力学因素在预防和治疗骨质疏松起重要作用。Osteoporosis is a disease mainly of the elderly. A study of the effect of agedness on osteoporos is made. The simulation of osteoporosis due to agedness factor is been realized in computer with the model combined finite element method. Results show that when persons grow old, outside loads decline as a result of fall ~ft muscle force and decrease of quantity of activity . When percentage of loss of bone mass to peak value bone mass is above 25, osteoporosis happens. Agedness factor can result in osteoporosis. This indicates the importance of mechanical factor in preventing and curing osteoporosis.

关 键 词：生物力学 骨质疏松 骨再造 模拟 老年人 

分 类 号：R318[医药卫生—生物医学工程]