孕中期羊水中细胞研究进展  

Progresses in the study of amniotic fluid cells

作　　者：李现铎[1] 陈方[1] 

机构地区：[1]上海第二医科大学附属新华医院泌尿外科,200092

出　　处：《国际生物医学工程杂志》2006年第2期106-109,共4页International Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(30271351)

摘　　要：孕中期羊水中细胞培养和核型鉴定广泛应用于产前诊断领域,可以发现一系列胎儿发育异常。近来,许多研究表明羊水中含有胎儿的干细胞,这些细胞能否应用于干细胞和组织工程学领域成为研究热点。综述了羊水中细胞的组成、来源、生物学特性、干细胞特性及组织工程学应用等方面的内容,并对研究前景进行展望。Amniotic fluid cells are used for prenatal diagnosis of a wide rang of fetal abnormalities caused by genetic mutations. Recent observations on cell cultures from amniotic fluid obtained by second-trimester amniocentesis provide evidence that they may represent a new source for the isolation of muhipotent stem cells. In this paper we reviewed the compose of amniotic fluid ceils and their origin, biological characteristic, muhipotent stem cells, and their prospects of application in tissue engineering.

关 键 词：羊水细胞 多能干细胞 组织工程 

分 类 号：R714[医药卫生—妇产科学]