正交实验法优化羧基纳米磁性粒子的合成条件  

Preparation of Carboxylated Magnetic Nanoparticles by Orthogonal Experimental Design

作　　者：单志[1] 杨婉身[1] 张旭[1] 黄乾明[1] 叶辉[2] 

机构地区：[1]四川农业大学生命科学与理学院,四川雅安625014 [2]温州医学院基础医学院,浙江温州325000

出　　处：《绵阳师范学院学报》2006年第2期56-59,共4页Journal of Mianyang Teachers＇ College

基　　金：四川省教育厅自然科学科研重点项目(2005A033)

摘　　要：采用正交实验方法,以引发剂、功能单体和铁氧体的量及搅拌速度为考察因素,粒子磁响应性和粒径为考察指标,优选出羧基修饰的高分散性纳米磁性粒子的合成条件。结果表明：转速和功能单体添加量为主要影响因素；当铁氧体1．4g,过氧苯甲酰138mg,甲基丙烯酸1ml,转速300r/min时可得到平均粒径11nm、分布系数0．46的强磁性纳米粒子。Orthogonal test method was employed to optimize the best condition for the preparation of carboxylated magnetic nanoparticles. The concentration of initiator, monomer, iron oxide and the rotating speed were considered as influencing factors and the results were evaluated by particle size and specific magnetization. It shows that under optimal condition of rotating speed 300r/min, iron oxides 1.4g, BPO 138mg, MAA lml, highly dispersive magnetic nanoparticles with an average diameter of - 11nm and distribution ratio of 0.46 was obtained.

关 键 词：正交实验 纳米磁性粒子 超顺磁性 分散聚合法 

分 类 号：Q64[生物学—生物物理学]