老年糖尿病与胰岛素抵抗综合征  

Elder diabetes patients and insulin resistance syndrom∶oral glucose tolerance test for 1551 subjects

作　　者：朱良湘[1] 刘元涛[1] 袁申元[1] 陈建文[1] 潘素芳[1] 袁明霞[1] 付汉菁[1] 

机构地区：[1]北京同仁医院微循环糖尿病科

出　　处：《实用老年医学》1996年第4期172-174,共3页Practical Geriatrics

摘　　要：对北京地区１５５１人进行口服葡萄糖耐量试验（ＯＧＴＴ）及胰岛素抵抗有关因素调查的结果表明：肥胖组随着年龄的增长，空腹及ＯＧＴＴ餐后２小时血浆胰岛素水平呈上升趋势，但是在非肥胖组未显示出相同的趋势。高血压的患病率也随增龄而增长，而在同一年龄组内，仅在老年前期组及老年组高血压患病率呈增高的趋势伴随有血糖状态的变化。以ＮＩＤＤＭ组最高（Ｐ＝０．０２７），以年龄的连续变量为因变量，经多元逐步回归分析结果表明：冠心病、高血压及血胆固醇与年龄的变化呈现显著的相关性（Ｐ＜０．０５）。The study on OGTT and factors related to insulin resistance in 1551 individuals was carried out in Beijing Area.The results showed that in the non obese group,the average fasting insulin level was higher in subjects with age≥65 years,compared with those age<65 years (0.060±0.02 vas 0.0433±0.03mmol/L respectively. P <0.001),The same tendency was also found in the obese group. According to the result of OGTT,subjects with age≥65 years were stratified into three subgroups :normal OGTT,IGT and NIDDM.The prevalence of hypertension was 35.6%,42.4% and 64.1% respectively ( P =0.027). Mutiple linear regression analysis was carried out with continue variable age as dependent variable and prevalence of CVD,hypertension,plasma total cholestrol,triglyceride,BMI and fasting plasma insulin as independent variables.The results showed a significant positive correlation between age and prevalence of CVD and hypertension and plasma cholesterol( P <0.05).

关 键 词：糖尿病 X综合征 胰岛素抵抗 冠心病 老年人 

分 类 号：R587.1[医药卫生—内分泌]