足月新生儿继发性呼吸窘迫综合征18例  

Clinical Analysis of Secondary Respiratory Distress Syndrome in 18 Full - Term Infants

作　　者：陈朝红[1] 韩玉昆[2] 卢光进[1] 叶贞志[1] 周北燕[1] 肖善秋[1] 

机构地区：[1]深圳市宝安妇幼保健院新生儿科,广东深圳518133 [2]中国医科大学第二临床医院新生儿科,沈阳110004

出　　处：《实用儿科临床杂志》2006年第10期613-614,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的探讨足月儿继发性呼吸窘迫综合征(RDS)的病因及临床表现。方法根据欧美新生儿急性RDS的诊断标准, 诊断18例足月儿继发性RDS。对其原发病、临床表现、血气分析、胸片、治疗及预后等资料进行分析。结果原发病主要是窒息 (14例),其次是吸入(11例);发病时间≤3 h 17例(94．4％);主要表现为生后不久即出现进行性呼吸困难,发绀,双肺呼吸音低并可闻及细湿啰音;氧合指数均低于200mm Hg,胸片具备快速多变的特点。治疗后痊愈、好转者16例(88.9％)。结论本病发病时间均较早,多数有围生因素。氧合指数均低,肺部X线变化快,与成人型RDS极为相似。早期发现、尽早行正压通气,多数患儿预后良好。Objective To investigate the etiology and clinical manifestation of secondary respiratory distress syndrome in full - term infants. Methods According to the diagnostic criteria of acute respiratory distress syndrome （ARDS） in European American Consensus Conference on ARDS, the clinical manifestation etiology, incidence, blood gas analysis and chest X - ray film were analyzed in 18 full - term infants treated with mechanical ventilation since June 1998 to September 2005. Results The basic diseases were asphyxia and aspiration, mainly the onset time≤3 h after birth, the clinical manifestation were progressive respiratory distress, cyanosis, pulmonary tales, oxygen index less than 200 mm Hg. After treatment, 16 （88.9%） cases were cured and improved. Conclusions The onset time of the disease is earlier, there are perinatal factor in most cases, oxygen index is lower, chest X - ray film manifestation changes fastly, as same as adult respiratory distress syndrome. Prognosis of most infants are benign if diagnosis and treatment with mechanical ventilation earlier.

关 键 词：呼吸窘迫综合征 继发性 病因 临床表现 足月新生儿 

分 类 号：R722.1[医药卫生—儿科]