人工肾病人血清乙肝两对半的检测及临床意义  

THE CLINICAL SIGNIFICANCE AND DETECTION OF SERA HBV MARKER IN ARTIFICIAL KIDNEY DEPARTMENT PATIENTS

作　　者：陈敏静[1] 李珩[1] 宁秋[1] 

机构地区：[1]广东省人民医院,广东广州510080

出　　处：《现代医院》2006年第5期63-64,共2页Modern Hospitals

摘　　要：目的 对广东省人民医院人工肾病区的病人血清进行乙肝两对半的检测。调查其感染情况并分析原因，以达到进一步采取预防措施，防止血透患者感染乙肝。方法 收集2005年6月～2005年10月在本院人工肾病区进血液透析的患者共205例，对其进行乙肝两对半检测，与其入院时的乙肝两对半结果进行比较分析，分析其可能感染的原因及感染情况。结果 初始血透治疗前感染乙肝病毒者共56例，乙肝两对半全阴者为89例。现检测结果为：56例乙肝患者不变，但是89例乙肝两对半全阴者中有15例出现HBsAg阳性，占16．8％，其余64例仍为乙肝两对半全阴。15例出现HBsAg阳性患者接受血透治疗平均为3．2年，13例有输血史，与64例仍为乙肝两对半全阴者相比有显著性差异，有输血史的患者亦显著增加（P〈0．05）。结论 与普通人群相比，血透患者感染HBV的危险性相当大，可能与其血透过程及输血有很大的关系。Objective Detect sera HBV marker in artificial kidney department patients of Guangdong provincial people＇s hospital to investigate the prevalence and cause, in order to prevent transmission of HBV infections among chronic hemodialysis （HD） patients. Methods Detect the HBV marker of 205 uremia patients in artificial kidney from June to September. Compared the result with those before their entrance of artificial kidney department. To investigate their prevalence and cause. Results Before chronic hemodialysis, 56 patients were HBV positive, 89 patients were HBV negative. After HD, 56 patients kept positive while 15 of the 89 HBV negative patients turned into HBV positive. The 15 patients received an average of 3.2 years HD therapy, and 13 of them had history of blood transfusion. There were significant differences between the 15 patients and the rest 64 of HD （p 〈0.05） and also between the patients with and without history of blood transfusion （p 〈 0.05）. Conelusion Chronic HD patients have a higher risk of HBV infection, they maybe infected by HD or blood transfusion.

关 键 词：人工肾 血液透析 乙肝 血清 

分 类 号：R512.62[医药卫生—内科学] R512.8[医药卫生—临床医学]