Novel Terbium Chelate Doped Fluorescent Silica Nanoparticles  

作　　者：宁巧玉 孟建新 王海鸣 刘应亮 满石清 

机构地区：[1]Institute of Nano-Chemistry, Department of Chemistry, Jinan University, Guangzhou 510632, China [2]Institute

出　　处：《Journal of Rare Earths》2006年第2期193-196,共4页稀土学报（英文版）

基　　金：ProjectsupportedbytheNationalScienceFoundationofChina(20475021)andScienceFoundationTeamProjectofGuang-dongProvince(05200555)

摘　　要：Novel terbium chelate doped silica fluorescent nanoparticles were prepared and characterized. The preparation was carried out in water-in-oil （W/O） microemulsion containing monomer precursor （pAB-DTPAA-APTEOS）, Triton X-100, n-hexanol, and cyclohexane by controlling copolymerization of tetraethyl orthosilicate and 3-aminopropyl-triethyloxysilane. The nanoparticles are spherical and uniform in size, about 30 nm in diameter, strongly fluorescent, and highly stable. The amino groups directly introduced to the surface of the nanoparticles using APTEOS during preparation made the surface modification and bioconjugation of the nanoparticles easier. The nanoparticles are expected as an efficient timeresolved luminescence biological label.Novel terbium chelate doped silica fluorescent nanoparticles were prepared and characterized. The preparation was carried out in water-in-oil （W/O） microemulsion containing monomer precursor （pAB-DTPAA-APTEOS）, Triton X-100, n-hexanol, and cyclohexane by controlling copolymerization of tetraethyl orthosilicate and 3-aminopropyl-triethyloxysilane. The nanoparticles are spherical and uniform in size, about 30 nm in diameter, strongly fluorescent, and highly stable. The amino groups directly introduced to the surface of the nanoparticles using APTEOS during preparation made the surface modification and bioconjugation of the nanoparticles easier. The nanoparticles are expected as an efficient timeresolved luminescence biological label.

关 键 词：TERBIUM MICROEMULSION fluorescent nanoparticles rare earths 

分 类 号：TB383.1[一般工业技术—材料科学与工程]