广西壮族自治区壮、汉族健康人群跟骨超声骨密度的比较  

Comparison of calcaneus ultrasound bone mineral density for healthy Zhuang and Han nationalities subjects in GuangXi

作　　者：朱自强[1] 徐成丽[1] 刘伟[1] 韩少梅[1] 祖淑玉[1] 朱广瑾[1] 

机构地区：[1]中国医学科学院中国协和医科大学基础医学研究所,北京100005

出　　处：《基础医学与临床》2006年第5期481-484,共4页Basic and Clinical Medicine

基　　金：国家科技部公益性专项基金重点项目(2002DIA40018)

摘　　要：目的获得广西壮族自治区壮、汉族各年龄组跟骨超声骨密度的正常值范围,比较分析壮、汉族骨峰值与骨质疏松患病率之间的差异,为该地区骨质疏松的诊断和预防提供科学依据.方法采用美国Lunar公司的AchillesExpress跟骨超声骨密度测定仪,对广西壮族自治区1646例（壮族男/女：350/441,汉族男/女：357/498）11～61岁健康志愿者进行跟骨超声硬度指数（SI）测定.按不同民族、性别、年龄进行分组,每10岁为一个年龄组,男、女各分5组,对数据进行统计分析.结果壮、汉族男、女跟骨超声骨密度呈现相似的变化规律,各年龄组骨密度均未见显著差异.男、女跟骨SI均在21～30岁年龄组达到峰值,之后均开始下降.壮、汉族男、女各年龄组骨质疏松患病率无显著差异.结论使用定量超声技术获得广西壮族自治区壮、汉族男、女健康人群跟骨SI值参考值范围,对骨质疏松的诊治具有重要意义.壮、汉族男、女峰值骨密度水平及骨质疏松患病率均无显著差异.Objective To obtain the reference ranges and to evaluate the differences of calcaneus ultrasonic bone mineral density （BMD） and the prevalence rate of osteoporosis between Zhuang and Han nationalities in GuangXi Autonomous Region, and to provide scientific foundation for osteoporotic diagnosis and prevention. Methods Stiff- ness index （SI） of calcaneus in 1646 healthy subjects （Zhuang nationality males/females =350/441; Han nationality males/females = 357/498） was measured with Achilles Express ultrasound densitometer. According to their nationality, gender, and age, all subjects were divided into different subgroups by ten years. Results Similar changes of calcaneus ultrasound BMD have been observed between Zhuang and Han nationalities males and females. The peak value of SI in Zhuang and Han nationalities of both sexes appeared in 21 - 30 age group. After reaching the peak value, SI value began to decline with age. No significant differences in the prevalence rate of osteoporosis between Zhuang and Han nationalities people were found. Conclusions The reference ranges of calcaneus SI in Zhuang and Han nationalities people of GuangXi were obtained with quantitive ultrasound （QUS） technique, which provided a reference of diagnostic criteria of osteoporosis for clinic and epidemiology. There was no significant differences in the prevalence rate of osteoporosis between healthy Zhuang and Han nationalities people.

关 键 词：跟骨 骨峰值 硬度指数 骨质疏松 

分 类 号：R445.1[医药卫生—影像医学与核医学] R589.5[医药卫生—诊断学]