甲真菌病危险因素的病例对照研究  

A Case-control Study on Risk Factors for Onychomycosis

作　　者：胡燕[1] 杨莉佳[1] 魏聆[1] 张海平[1] 戴迅毅[1] 华海康[1] 戚稼[1] 孙慧[1] 

机构地区：[1]无锡市第二人民医院皮肤科,江苏无锡214002

出　　处：《中国皮肤性病学杂志》2006年第5期278-280,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨甲真菌病发病可能的危险因素。方法对175例甲真菌病患者进行1∶1配比的病例对照研究,采用单因素和多因素的条件Logistic回归分析。结果甲真菌病发病与下列9个因素密切相关:足癣(OR=10.502),手癣(OR=9.991),长期用广谱抗生素、皮质类固醇、免疫抑制剂治疗(OR=7.180),潮湿的生活或工作环境(OR=5.167),家族史(OR=2.687),甲外伤(OR=2.668),公用拖鞋、擦脚布、脚盆(OR=2.081),手足多汗(OR=1.955)、勤换鞋袜(OR=0.324)。结论足癣,手癣,长期用广谱抗生素、皮质类固醇、免疫抑制剂治疗,潮湿的生活或工作环境,家族史,甲外伤,公用拖鞋、擦脚布、脚盆,手足多汗是甲真菌病发病的危险因素,勤换鞋袜为甲真菌病的保护因素。Objective To investigate the potential risk factors for onychomycosis. Methods 175 cases with onychomycosis were conducted by a 1 ： 1 matched case-control study. Data were analyzed by a single-factor and multifactor conditional logistic retress analysis. Results Muhifactor conditional logistic regression model indicated that the episode of onychomycosis were significandy correlated with tinea pedis （ OR = 10.502）, tinea marius （ OR = 9.991 ）, using broad - spectrum antibiotic, corticosteroid and immuno-suppressive drugs for a long time （ OR = 7. 180）, the wet environment of living and work（ OR = 5. 167） ,family history（ OR = 2.687 ）, nail trauma（ OR = 2.668 ）, public using slippers, wipe feet cloth and feet-basin （ OR = 2.081 ）, extremity hyperhidrosis （OR = 1.955） ,changing footgear frequently（OR =0.324）. Conclusion Tinea pedis,tinea marius,using broad-spectrum antibiotic,corticosteroid and immuno-suppressive drugs for a long time,the wet environment of living and work,family history,nail trauma, public using slippers, wipe feet cloth and feet-basin, extremity hyperhidrosis were risk factors for onychomycosis ;changing footgear frequently was protective factor.

关 键 词：甲真菌病 危险因素 病例对照研究 

分 类 号：R756.4[医药卫生—皮肤病学与性病学]