院前溶栓对肌钙蛋白T和肌红蛋白升高且ST段抬高的急性冠脉综合征的疗效观察  

The therapeutic effect of pre-hospital vein thrombolytion on acute coronary syndromes with myoglobin and cardiac troponin T increasing and ST elevation

作　　者：梁俊雄[1] 梁棕[1] 吕博文[1] 张剑峰[1] 赵德明[1] 李荣杰[1] 

机构地区：[1]广东省江门市新会人民医院急诊科,广东江门529100

出　　处：《赣南医学院学报》2006年第2期233-234,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：目的:探讨院前溶栓对肌钙蛋白T和肌红蛋白升高且ST段抬高的急性冠脉综合征(ACS)的疗效观察及临床意义。方法:选取院前肌钙蛋白T和肌红蛋白升高且ST段抬高的急性冠脉综合征患者48例,治疗组24例,予院前尿激酶静脉溶栓,对照组24例,院前不予溶栓,其他抢救措施不受限制,追踪所有患者住院期间冠脉再通情况及TIM I分级和短期内心脏事件的发生情况及预后。结果:治疗组冠脉再通情况明显优于对照组(P<0.01),短期心脏事件发生明显减少(P<0.05)。结论:院前静脉溶栓可以提高肌钙蛋白T和肌红蛋白升高且ST段抬高的ACS的血管再通率,减少短期心脏事件的发生,改善预后。Objective： To explore the therapeutic effect and clinical value of pre-hospital vein thrombolytion on acute coronary syndromes（ACS） with myoglobin and cardiac troponin T increasing and ST elevation. Method： 48 patients with ACS and both myoglobin and cardiac troponin T increasing pre - hospital were divided into therapeutic group（ n = 24） and control group（ n= 24）. The therapeutic group were treated with urokinase in vein thrombolytion pre-hospital, other rescue measures were not limited in two groups. Coronary artery perforation and recent subsequent cardiac events were followed up in both groups. Result ： There were far better of coronary artery perforation in therapeutic group than those in control group （ P 〈 0.01 ）. Recent subsequent cardiac events were less in therapeutic group than in control group（ P 〈 0.05 ）. Conclusion： Pre-hospital vein thrombolytion on ACS with myoglobin and cardiac troponin T increasing and ST elevation can improve coronary artery perforation rate, decrease recent subsequent cardiac events, and made prognosis of those patients better.

关 键 词：急性冠脉综合征 肌红蛋白 肌钙蛋白T 院前溶栓 

分 类 号：R446.1[医药卫生—诊断学]