糖尿病合并急性冠状动脉综合征患者冠状动脉病变的对比分析  

The contrast analysis of coronary artery pathological changes in diabetic patients with acute coronary syndrome

作　　者：陈忠[1] 张善春[2] 张德铭[2] 黄自平[2] 

机构地区：[1]天津市第三医院急诊科,天津300250 [2]天津市第三医院心内科,天津300250

出　　处：《华夏医学》2006年第2期182-184,共3页Acta Medicinae Sinica

摘　　要：目的:了解糖尿病(DM)合并急性冠状动脉综合征(ACS)患者冠状动脉病变的特征。方法:冠心病监护病房收治的38例空腹血糖≥7.0mm o l/L的ACS患者(DM组),同期选择性别、年龄、吸烟、高血压、心脏肌钙蛋白和心肌梗死史相匹配的糖耐量正常的47例作为对照的ACS患者(NDM组),分别对两组进行冠状动脉造影分析及比较。结果:①DM组较NDM组血纤维蛋白原、空腹血糖、甘油三酯浓度高(P均<0.05);而高密度脂蛋白胆固醇DM组较NDM组低(P<0.05)。②DM组较NDM组冠状动脉单支病变发生率低(23.68%比44.68%,P<0.05);而多支病变的发生率高(44.73%比19.15%,P<0.05)。结论:DM并ACS患者的冠状动脉病变范围广泛,DM发生ACS是多因素协同的结果。Objective： To determine coronary artery pathological changes in diabetic patients with acute coronary syndromes（ACS）. Methods： 38 patients with ACS that were admitted in hospital and blood glucose that did not have a meal ≥17.0 mmol/L （DM group）, same period choice was with 47 controls matched with ACS patients for sex, age range （＋2 yrs）, smoke cigarette, serum cardiac troponin, hypertension and myocardial infarction history. The con- trast analysis of coronary angiographic findings were carried out in these patients. Results： ① Serum fibrinogen, blood glucose and serum lipid concentration in DM group was markedly higher than that of NDM group（P〈0. 05）. ② Than NDM group, DM patients with ACS had more extensive coronary artery disease and were more likely to have triple vessel coronary artery disease （44. 73% to 19.15%,P〈0. 05）, whereas DM patients with ACS were more likely to have single coronary artery pathological changes. Conclusion： Coronary artery pathological changes is extensive in ACS diabetes patients. ACS is resulted from the conjunction of many factors.

关 键 词：糖尿病 心肌缺血 心肌梗死 

分 类 号：R587.2[医药卫生—内分泌] R541.4[医药卫生—内科学]