Electron Transfer Reaction Between Desoxyadenosine and Triplet 2-Methyl-1,4-naphthaquinone:A Laser Photolysis Study  

作　　者：MA Jian-hua LIN Wei-zhen HAN Zhen-hui YAO Si-de LIN Nian-yun 

机构地区：[1]College of Biology Engineering, Jimei University, Xiamen 361021, P. R. China [2]Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, P. R. China

出　　处：《Chemical Research in Chinese Universities》2006年第3期397-399,共3页高等学校化学研究（英文版）

基　　金：SupportedbytheNationalNaturalScienceFoundationofChina(No.20133020)andPhotoScience&TechnologyResearchFoundationofScienceandTechnologyCommitteeofShanghaiandInvestigationFundofCommitteeofEducationofFujianProvince(No.JA03134).

摘　　要：Introduction Electron transfer oxidation of DNA by triplet artificial photonuclease reveals a bright prospect of its application in biology and medicine. Both molecular orbital calculation and laser experiments have indicated that the homo guanine sequence should be the final localization site of photoexcited hole via long range migration within DNA. However, the direct observation of the produced ion pairs of biomolecules especially the stabilized radical cation DNA or its components is hampered by the overwhelming transient absorption of protonated radical anion of photosensitizers, such as 2-methyl-1,4-naphthaguinonel （MQ）.Introduction Electron transfer oxidation of DNA by triplet artificial photonuclease reveals a bright prospect of its application in biology and medicine. Both molecular orbital calculation and laser experiments have indicated that the homo guanine sequence should be the final localization site of photoexcited hole via long range migration within DNA. However, the direct observation of the produced ion pairs of biomolecules especially the stabilized radical cation DNA or its components is hampered by the overwhelming transient absorption of protonated radical anion of photosensitizers, such as 2-methyl-1,4-naphthaguinonel （MQ）.

关 键 词：Electron transfer reaction 2-Methyl-1 4-naphthaquinone Desoxyadenosine Laser photolysis 

分 类 号：Q525[生物学—生物化学] Q503