早期新生儿黄疸与红细胞锌和血浆锌  

Early neonatal jaundice with zinc in red blood cell and plasma zinc.

作　　者：易海英[1] 徐舒[1] 王少敏[2] 邓香兰[1] 王艳华[1] 杨树杰[1] 左华凯[1] 刘志刚[2] 

机构地区：[1]孝感市中心医院儿科,湖北孝感432000 [2]孝感市中心医院检验科,湖北孝感432000

出　　处：《临床和实验医学杂志》2006年第4期382-383,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的研究新生儿黄疸与新生儿及母亲红细胞锌和血浆锌的关系。方法利用原子吸收分光光度法测量248例足月新生儿及其母亲红细胞锌与血浆锌,并测定248例新生儿血胆红素值。结果①新生儿高胆红素组与低胆红素组红细胞锌浓度分别为(23.1+8.4)μmol/L,(31.4+9.8)μmol/L,两组间比较差异有极显著性(P<0.01),血浆锌浓度分别为(15.6+6.8)μmol/L,(16.2+7.4)μmol/L,两组间比较差异无显著性(P>0.05)。②两组母亲红细胞锌浓度分别为(185.3±22.2)μmol/L,(203.5±23.5)μmol/L,两组间比较差异有极显著性(P<0.01),血浆锌浓度分别为(15.5±5.1)μmol/L,(14.8±5.6)μmol/L,两组间比较差异无显著性(P>0.05)。结论高胆红素血症发生与红细胞锌水平有关,与血浆锌无关。Objective To study the relationship between neonatal jaundice with zinc concentration in red blood cell and plasma zinc of infant and mother. Methods The zinc concentration in red blood cell and plasma of 248 full - term infants and the mothers were determined by atonic absorption spectrometry,the infant＇s bilirubin levels were also measured, Results ① Significant difference（ P 〈0.01 ）of red blood cell zinc concentration was revealed between infants with higher bilirubin level （ 23.1 ± 8.4）μmol/L and lower bilirubin level （31.4 ± 9.8 ） μmol/L. No significant difference（ P 〉 0.05 ）of plasma zinc concentration was revealed between infants with higher biliruhin level （15.6 ± 6.8 ）μmol/L and lower bilirubin level （16.2 ± 7.4） μmol/L. ② Significant difference （ P 〈 0.01 ）of red blood cell zinc concentration was revealed between the mothers whose infants with higher biliruhin level （185.3±22.2）μmol/L and the mothers whose infants with lower hiliruhin level （203.5±23. 5 ） μmol/L. No significant difference（ P 〉 0.05 ）of plasma zinc concentration was revealed between the mothers whose infants with higher hilirubin level （ 15.5 ± 5.1 ）μmol/L and the mothers whose infants with lower bilirubin level （ 14.8 ± 5.6）μmol/L. Conclusion Hyperbilibubin associated closely with the zinc concentration in red blood cell, but not associated with plasma zinc.

关 键 词：新生儿 黄疸 红细胞 血浆 锌 

分 类 号：R722.1[医药卫生—儿科]