海南含羞草中黄酮碳苷类化学成分的研究  

Chemical constituents of C-glycosylflavones from Mimosa pudica

作　　者：袁珂[1] 吕洁丽[2] 殷明文[3] 

机构地区：[1]浙江林学院食品与药学院,浙江临安311300 [2]河南中医学院药学院,河南郑州450008 [3]郑州大学化学系,河南郑州450052

出　　处：《药学学报》2006年第5期435-438,共4页Acta Pharmaceutica Sinica

摘　　要：目的研究海南含羞草(M im osa pudica)的化学成分。方法利用D iaion HP-20,Toyopearl HW-40,MC I-Gel CHP-20,Sephadex LH-20,RP18及硅胶等柱色谱法对海南含羞草成分进行分离纯化,根据理化性质和光谱数据鉴定化合物的结构。结果分离鉴定了4个化合物:7,8,3,′4′-四羟基-6-C-[α-L-鼠李糖-(1→2)]-β-D-葡糖黄酮碳苷(I),5,7,4′-三羟基-8-C-[α-L-鼠李糖(1→2)]-β-D-葡糖黄酮碳苷(II),5,7,3,′4′-四羟基-6-C-[α-L-鼠李糖-(1→2)]-β-D-葡糖黄酮碳苷(III),儿茶素(IV)。结论化合物I为新化合物,化合物II^IV为首次从该植物中分离得到。Aim To study chemical constituents of Mimosa pudica of Hainan province. Methods The constituents were separated and purified by column chromatography with macroporous adsorption resin Diaion HP-20, Sephadex LH-20, Toyopearl HW-40, MCI Gel CHP-20, RP-18 and normal phase silica gel. Their structures were identified on the basis of physical and spectral data. Results Four compounds were isolated and identified as： 7,8,3＇,4＇-tetrahydmxyl-6-C-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyranosyl flavone （Ⅰ）; 5,7,4＇-tetrahydmxyl-8-C-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyranosyl flavone （Ⅱ）; 5,7,3＇,4＇-tetrahydmxyl-6-C-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyranosyl flavone （Ⅲ）; catcher （Ⅳ）. Conclusion Compound Ⅰ is a new compound and componuds Ⅱ-Ⅳ were isolated from this plant for the first time.

关 键 词：含羞草 7 8 3' 4'-四羟基-6-C-[α-L-鼠李糖-(1→2)]-β-D-葡糖黄酮碳苷 黄酮碳苷 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]