河蚌多糖提取优化工艺的研究(英文)  

Optimum extraction process of mussel polysaccharide

作　　者：沈鸿[1] 彭蕴茹[2] 窦昌贵[3] 

机构地区：[1]南京脑科医院,江苏南京210029 [2]江苏省中医药研究所,江苏南京210038 [3]中国药科大学中医药研究所,江苏南京210038

出　　处：《中成药》2006年第5期746-748,共3页Chinese Traditional Patent Medicine

摘　　要：目的:对河蚌多糖的提取工艺进行优化,从而提高多糖的含量。方法:本文采用正交设计的方法,以硫酸蒽酮法测定总糖含量为评价指标,从提取温度、NaOH浓度、提取次数等因素入手,进行正交优化试验。结果:提取温度、NaOH浓度为有极显著意义的因素,提取次数对多糖的含量影响不大,综合考虑,最佳提取工艺为A1B2C1即在4℃时,NaOH浓度为5%,提取1次。结论:优选得到的工艺经济,简单、稳定、可行。AIM ： To ： optimize the extraction process of mussel polysaccharide, and then gain higher content of polysaccharide. METHODS： Involved in the three factors, temperature and times of extraction, concentration of NaOH solutions, to do the experiment by orthogonal design uniform design and the method of anthrone. RESULTS： The result showed that the most important factors were temperature of extraction and concentration of NaOH solutions. The optimum extraction conditions were A1B2C1 , 4℃, 5% NaOH solutions and extracting only once. CONCLUSION： This optimized process is economical, simple, stable and efficient.

关 键 词：河蚌多糖 正交设计 硫酸蒽酮法 

分 类 号：R284.2[医药卫生—中药学]