止泻灵胶囊身体依赖性的实验研究  

Experimental study on physical dependence of Zhixieling Capsule

作　　者：姚世霞[1] 宋京都[2] 倪京满[1] 

机构地区：[1]兰州大学药学院,兰州730000 [2]甘肃省药品检验所,兰州730000

出　　处：《中药新药与临床药理》2006年第3期181-183,共3页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：目的研究中药制剂止泻灵胶囊的身体依赖性。方法采用小鼠跳跃实验、大鼠催促和大鼠自然戒断试验对止泻灵胶囊进行身体依赖性试验。结果止泻灵胶囊在实验中均未出现明显戒断症状。结论止泻灵胶囊无身体依赖性。Objective To evaluate the physical dependence of Zhixieling capsule. Methods The physical dependence of Zhixieling capsule was observed by mouse jump test, rat precipitation test and rat natural withdrawal test. Results Zhixieling capsule showed no obvious withdrawal symptoms. Conclusion Zhixieling capsule has no physical dependence.

关 键 词：止泻灵胶囊 身体依赖性 吗啡 氢溴酸烯丙吗啡 

分 类 号：R285.5[医药卫生—中药学]