温度敏感性PVP/CHI共混水凝胶的制备与溶胀性能  

Preparation and Swelling Performance of Thermosensitive PVP/CHI Blend Hydrogel

作　　者：易国斌[1] 康正[1] 崔亦华[1] 郭建维[1] 杨少华[1] 

机构地区：[1]广东工业大学轻工化工学院,广东广州510006

出　　处：《化学与生物工程》2006年第5期20-22,共3页Chemistry & Bioengineering

基　　金：广州市科技计划项目(2001-Z-103-01);广东省教育厅自然科学基金资助项目(Z02030)

摘　　要：制备了戊二醛交联的PVP/CHI共混水凝胶,讨论了CHI∶PVP(质量比)、引发剂用量、交联剂用量、反应温度等主要条件对凝胶溶胀性能的影响。温度敏感性实验表明,凝胶分别在33℃、37℃出现最大平衡溶胀率,即具有多重温度敏感性。随着PVP含量的升高,凝胶在33℃时对温度的敏感程度升高、37℃时对温度的敏感程度降低,交联度增加使凝胶的温度敏感程度降低。另外,PVP含量升高使CHI结晶度降低,进而使PVP/CHI凝胶的玻璃化转变温度Tg降低。Polyvinylpyrrolidone （PVP）/Chitosan （CHI） blend hydrogel is prepared with glutaraldehyde as crosslinking agent. Influences of main factors such as CHI ： PVP, initiator content, crosslinking agent content and reaction temperature on swelling performance of the hydrogel are discussed. Top equilibrium swelling rate （ESR） is obtained at about 33℃ and 37℃ respectively from thermosensitivity experiments and it is suggested that the hydrogel shows multithermosensitivity. Furthermore, with increasing of PVP content, thermosensitivity of the hydrogels seems more significantly at 33℃ or so but less significantly at 37℃ or so or with increasing of crosslinking degree. The glass-transition temperature（Tg） decreases with increasing of PVP content because crystalline degree of CHI is decreased.

关 键 词：PVP/CHI共混水凝胶 温度敏感性 多重敏感性 玻璃化转变温度 

分 类 号：TQ317[化学工程—高聚物工业]