μ型阿片受体研究进展  

作　　者：吴雪 刘东武[2] 牟洪善[3] 

机构地区：[1]山东单县第二人民医院外科,单县274329 [2]山东师范大学生命科学学院,济南250014 [3]鲁东大学生命科学学院,烟台264025

出　　处：《生命科学仪器》2006年第2期22-24,共3页Life Science Instruments

摘　　要：μ型受体主要分为μ1型和μ2型受体,μ型受体是吗啡等阿片类药物镇痛与成瘾的基础,其内源性配体为内吗啡肽,内阿片肽及其受体在循环休克的发生发展中起重要的介导作用,μ受体还参与了神经-内分泌-免疫网络调节和机体的镇痛机制,近年来,人们对μ型受体进行了基因克隆。The μ opioid receptor, is classified into two subtypes, μ 1 and μ 2. By binding with μ opioid receptor, morphine plays important roles in opioid analgesia and opioid addiction. The endormorphin can bind with μ opioid receptor in vivo. The nervous, incretionary and immune systems can exchange information through endogenous opioid peptides that can bind with opioid receptor. The μ opioid receptor also participates in shock of animals. Recently, the gene of μ opioid receptor has been cloned.

关 键 词：μ型受体 内阿片肽 

分 类 号：Q426[生物学—神经生物学]