耐多药肺结核经纤维支气管镜局部给药后支气管播散的观察  

Observation of bronchus dissemenate which created with bronchofiberscope by local injection on multi-drug resistance pulmonary tuberculosis

作　　者：陈慧冬[1] 周海翠 

机构地区：[1]湖北省武汉市结核病医院,湖北武汉430083

出　　处：《中国内镜杂志》2006年第5期490-492,共3页China Journal of Endoscopy

摘　　要：目的评价耐多药肺结核经纤维支气管镜(纤支镜)局部给药后支气管播散情况。方法78例耐多药肺结核均经纤支镜局部给药,配合全身化疗。分为两组,1组为无合并症者43例,2组为合并糖尿病者35例;对两组治疗后支气管播散情况观察并对照。结果2月后无合并症组支气管播散率7.0%,合并糖尿病组支气管播散率25.7%,两组播散率差异有显著性(P<0.05)。支气管播散病例主要集中于治疗开始的前2周内,合并糖尿病组支气管播散范围广泛。结论经纤支镜局部给药配合全身化疗治疗无合并症耐多药肺结核,支气管播散率低,安全可靠;治疗合并糖尿病的耐多药肺结核,支气管播散率高,需慎用。[Objective] To study bronchus dissemenate which created by local injection through bronchfiberscope on multi-drug resistance pulmonary tuberculosis. [Methods] 78 cases were treated by local injection through bronchfiberscope with chemotherapy. All cases were divide into two groups： the first group had 43 cases with no complications; the second group had 35 cases with diabetes. The bronchus dissemenate of the two groups were compared. [Rusults] By the end of two months, the dissemenate rate was 7.0% in the first group, the second group with cliabetes was 25.7%, which have significant differentce （P 〈0.05）. The cases with bronchus dissemenate were focus on the f＇rrst two weeks after therapy, and more extensive in the cases with diabetes. [Conclusion] By local injection through bmnchofiberscope with chemotherapy is safe and no higher bronchus dissemenate rate on multi-drug resistance ulmonary tuberculosis with no complications; it is higher in dissemenate rate in the cases with diabetes. It should be cautious to the cases with diabetes.

关 键 词：肺结核 纤维支气管镜 局部给药 糖尿病 插散 

分 类 号：R521[医药卫生—内科学]