极谱催化波测定脉络宁口服液中的肉桂酸  

Determination of Cinnamic Acid in Mailuoning Oral Liquid by Polarographic Catalytic Wave without Deoxygenation

作　　者：王福民[1] 

机构地区：[1]渭南师范学院化学化工系,陕西渭南714000

出　　处：《分析测试学报》2006年第3期64-67,共4页Journal of Instrumental Analysis

基　　金：陕西省教育厅专项科研基金资助项目(03JK216)

摘　　要：应用线性扫描极谱法（ISV）、循环伏安法（CV），在1．0mol／L HAc—NaAc（pH4．1）含溶解氧的支持电解质中，对内桂酸的电化学行为进行了研究。在该支持电解质中于-1．50V（vs.SCE）处发现肉桂酸产生一灵敏的催化极谱还原峰，其峰电流与肉桂酸的浓度在2．5×10^-6～7．5×10^-4moL／L范围内呈良好的线性关系（r=0．9991）；检出限为8．0×10^-7mol／L，对8．0×10mol／L的肉桂酸溶液进行11次平行测定，RSD为1．4％。并采用循环伏安法对肉桂酸的电极反应机理进行了探讨，结果表明该电极反应过程为不可逆过程。该方法已用于测定脉络宁口服液中的内桂酸。The electrochemistry behavior of cinnamic acid in 1.0 mol/L HAc - NaAc supporting electrolyte containing dissolved oxygen at pH 4. 1 was studied by linear scanning voltammetry and cyclic voltammetry, respectively. Under the supporting electrolyte, a sensitive, catalytic reduction peak of cinnamic acid was observed at the peak potential of - 1.50 V（vs. SCE）. The 2nd derivative polarographic peak current of the catalytic reduction wave of cinnamic acid has a linear relationship with its concentration ranging from 2.5×10^-6～7.5×10^-4moL/L with a correlation coefficient of 0. 999 1. The detection limit is 8.0×10^-7mol/Land the RSD（n = 11 ） is 1.4% at the concentration level of 8.0×10^-5 mol/L. The mechanism of electrode reduction reaction process was studied by cyclic voltammetry. The results show that the electrode reaction is an irreversible process. The proposed method has been applied to the determination of einnamic acid in Mailuoning oral liquid.

关 键 词：肉桂酸 脉络宁口服液 溶解氧 极谱催化波 循环伏安法 

分 类 号：O657.14[理学—分析化学] R927.2[理学—化学]