猪胰铁蛋白释放铁和磷酸盐的动力学特性  

Kinetic Characteristics of Iron and Phosphate Release from the Pig Pancreas Ferritin

作　　者：林志超[1] 陈平[1] 胡晓慧[1] 黄慧英[1] 黄河清[1] 

机构地区：[1]厦门大学生命科学学院生物化学与生物技术学系,福建厦门361005

出　　处：《厦门大学学报（自然科学版）》2006年第B05期50-53,共4页Journal of Xiamen University：Natural Science

基　　金：国家自然科学基金(30470372);厦门市科技项目基金(350Z2001263)资助

摘　　要：猪胰铁蛋白(p ig pancreas ferritin,PPF)铁核由179 phosphate/PPF和1698 Fe3+/PPF组成,平均磷铁比值为1∶9.5.PFF铁核表层由较高的磷铁比组成.选用电子光谱技术研究PPF释放铁和磷酸盐全过程,发现PPF以两种不同速率途径释放铁与磷酸盐.在弱酸条件下,PPF释放铁的速率明显高于在弱碱条件下的速率,证实PPF蛋白壳的柔性调节能力强弱是控制释放铁和磷酸盐速率的重要因素之一.The iron core of pig pancreas ferritin （PPF） is composed of 179 phosphates and 1698 Fe^3＋ per molecular PPF. The ratio of phosphate to iron within the PFF core is determined to be 1：9.5. The ratio on the surface of the iron core in PPF is higher than that in the inside of the core. A complete process of iron and phosphate releasing from the PPF is observed using electron spectra technique. The resuits showed that both the iron and phosphate veleasing presented two different rates. In weak acid medium, the releasing rate of iron in PPF is much faster than that in weak basic medium.

关 键 词：铁蛋白 猪胰 铁释放 动力学 磷酸盐 

分 类 号：Q75[生物学—分子生物学]