嗅感受细胞在不同气体浓度下的神经发放规律分析  

Spike response characteristics of olfactory receptor neurons to various odorants

作　　者：郭宏记[1] 童勤业[2] 

机构地区：[1]浙江大学物理系,浙江杭州310027 [2]浙江大学生物医学工程学系,浙江杭州310027

出　　处：《浙江大学学报（工学版）》2006年第5期853-857,共5页Journal of Zhejiang University：Engineering Science

基　　金：重大基础研究前期研究专项基金资助项目(2002CCA01800);国家自然科学基金资助项目(30170267)

摘　　要：针对分析神经脉冲编码的问题,采用H-H方程计算机分析的方法,以嗅感受细胞为例,用非线性动力学方法分析了神经脉冲序列产生过程、脉冲序列随输入信号变化而变化的规律,以及平均频率理论的适用范围.从非线性角度看,平均频率理论只适用于出现Hopf分叉的地方,也就是从分级电位变为动作电位的环节上,而且输入的分级电位必须是可排序信号,输出脉冲序列才能满足平均频率理论.这种情况一般都发生在感觉器官的最前的几个环节中,因此平均频率理论只适用于这几个环节.The H-H model was computed to research on neural spike coding. The product of neural spike sequences was analyzed with nonlinear dynamics in olfactory receptor. The law of the change of the sequence of neural spikes, the change of the input signal, and analyzed the applicability of mean rate coding hypothesis were researched. From the viewpoint of nonlinear theory, the mean rate coding hypothesis can only be applied when Hopf bifurcation arises and where localized graded potential turns into action potential. Besides output spike sequence will follow the mean rate coding hypothesis only when the inputs can be ordered by magnitude. This state only exists in sense organs, so mean rate coding hypothesis is suitable only here.

关 键 词：H-H方程 嗅感受细胞 神经信息编码 

分 类 号：Q339.12[生物学—遗传学]