二黄方治疗多发性硬化急性发作的临床观察  

Treatment of relapsing multiple sclerosis with Erhuang Formula

作　　者：樊永平[1] 王平[2] 张星虎[1] 龚海洋[1] 周莉[1] 刘秀贞[1] 王蕾[3] 

机构地区：[1]首都医科大学附属北京天坛医院,北京100050 [2]山东省滕州市中心人民医院,山东277500 [3]首都医科大学中医药学院,北京100069

出　　处：《北京中医药大学学报》2006年第4期273-276,280,共5页Journal of Beijing University of Traditional Chinese Medicine

基　　金：北京市中医药科技发展基金项目(No.2003Ⅲ-21);北京市中医药重点学科基金项目(No.2004京中重Ⅵ14);北京市自然科学基金项目(No.7062022)

摘　　要：目的观察经验方二黄方对多发性硬化急性发作期的临床疗效.方法将65例住院患者随机分为对照组（35例）和治疗组（30例）,对照组给予甲基强的松龙、强的松为主的常规西医治疗,治疗组在此基础上给予二黄方（熟地、生地、制首乌等组成）,每日1剂,连续3～4周.结果二黄方对患者的肢体麻木、疼痛有显著的改善作用,P＜0.001;对肢体瘫痪、视力障碍也有一定的改善作用,对二便障碍有潜在的优势;能明显降低激素引起的白细胞升高的比例.结论多发性硬化急性发作期在常规治疗的基础上结合使用二黄方,能有效改善患者神经症状,减少激素副作用,促进患者康复.Objective To observe the clinical effect of Erhuang Formula on relapsing multiple sclerosis. Method To divide randomly 65 cases of multiple sclerosis into the control group （ n = 35 ） and the treatment group （ n = 30 ）. The control group was treated with routine western medicine mainly with methylprednisolone and prednisone, and the treatment group was treated with Erhuang Formula besides of routine western medicine once a day for 3 or 4 weeks. Result Erhuang Formula relieved obviously acroagnosis and melagra （P 〈 0. 001 ） and acroparalysis and dysopia too. Erhuang Formula had a potential effect on aconuresis and encopresis. It also decreased the ratio of leukocylosis induced by hormones. Conclusion The treatment of relapsing multiple sclerosis with routine western medicine combined Erhuang Formula can relieve neurological symptoms, reduce side effects of hormones and improve the rehabilitation.

关 键 词：多发性硬化 二黄方 肝肾阴虚 痰瘀阻络 

分 类 号：R277.745.1[医药卫生—中医学]