预防性抗生素治疗与早产低体重儿院内感染相关性探讨  

The study of the relativity between nosocomial infection of the low birth weight premature infants and prophylactic use of antibiotics

作　　者：杨春芳[1] 张琼枝[1] 

机构地区：[1]安徽省立医院儿科,合肥230001

出　　处：《安徽医学》2006年第3期214-215,共2页Anhui Medical Journal

摘　　要：目的探讨早产低体重儿预防性应用抗生素治疗能否减少院内感染的发生。方法回顾性分析1998年1月至2003年1月我院儿科新生儿重症监护室(NICU)住院早产低体重儿,按其有无预防应用抗生素治疗分成两组。在护理常规、消毒隔离制度以及支持治疗相同的情况下,比较两组院内感染的发生率差异有无统计学意义。结果抗生素预防组院内感染发生率6.48%,未预防组院内感染发生率7.69%,两组院内感染发生率差异无显著性,P>0.05。结论对住院早产低体重儿预防性应用抗生素治疗是不必要的。Objective To study the possibility of lower the hospital infection rate among the low birth weight premature infants by prophyladic use of antibiotice. Methods From January 1998 to January 2003,the low birth weight premature infants adimitted to neonatal intensive care unit（NICU）were divided into two groups,prohylactic group and nonprophylactic group, we compared the hospital infecion rate of two groups under the same conditions, include sterile isolation precaution and supportive treatment. Results The hospital infection rate of the prophylactic group is 6.48% ,and the rate of the non- prophylactic group is 7.69 %. There is no signification difference between two groups（p〉0.05）. Conclusion It is not necessary to give the treatment of prophylactic use of antibiotics for the low birth weight premature infants.

关 键 词：早产12低出生体重 抗生素 院内感染 

分 类 号：R722.6[医药卫生—儿科] R563.1[医药卫生—临床医学]