剖宫产术后患者口服氟氯西林预防感染的疗效观察  

A Study of the Effect of Peroral Flucloxacillin in the Prevention of Infection after Cesarean Section

作　　者：罗惠娟[1] 李玮璟[1] 

机构地区：[1]暨南大学附属第一医院妇产科,广州510632

出　　处：《医药导报》2006年第6期534-535,共2页Herald of Medicine

摘　　要：目的观察剖宫产患者术后口服氟氯西林预防感染的效果。方法将剖宫产患者566例分为治疗组301例和对照组265例。治疗组术前30 m in内静脉注射头孢曲松1.0 g,术后给予口服氟氯西林胶囊0.5 g,b id,共5 d;对照组术前30 m in内静脉注射头孢曲松1.0 g,术后给予静脉注射头孢曲松1.0 g,qd,共3 d。其他处理两组相同。比较两组产褥感染的情况。结果治疗组和对照组产褥感染分别为34,19例,差异无显著性(P>0.05),且均无严重不良反应。结论无感染的剖宫产术后患者可口服氟氯西林预防感染,减少全身用药对母婴的影响,降低医疗费用。Objective To survey the effect of peroral flucloxacillin in the prevention of infection after cesarean section. Methods 566 predelivery women scheduled for cesarean section were divided into 2 groups ： the trial group （ n = 301 ） and control group（ n = 265 ）. Women of the trial group were given each an Ⅳ injection of 1.0 g of rocephin 30 min before the operation and 0.5 g of flucloxacillin capsules PO, b. i. d. after the operation for 5 consecutive days. Women of the control group were given each an IV injection of 1.0 g of rocephin after the operation for 3 consecutive days. Other managements for the parturients of the 2 groups during the perinatal period were similar. The incidence of puerperal infection in the 2 groups was compared. Results 34 and 19 cases of puerperal infection were diagnosed in women of the trial group and control group, respectively, the difference being insignificant （P 〉 0.05 ）. No adverse reactions of the drugs were encountered in the 2 groups. Conclusion Peroral flucloxacillin may be used in parturients after aseptic cesarean section for the prevention of infection and harmful effects of systemic medication on the mother and child as well as for the reduction of medical expense.

关 键 词：氟氯西林 头孢曲松 剖宫产 

分 类 号：R978.1[医药卫生—药品] R714.4[医药卫生—药学]