不同药物对柔红霉素血管外渗的防护作用  

Effect on different drugs to protect vascular exosmose of daunorubicin

作　　者：雷美容[1] 马晓玉[2] 冯晓敏[2] 柯晓燕[2] 

机构地区：[1]郧阳医学院 [2]郧阳医学院附属太和医院

出　　处：《护理研究（上旬版）》2006年第6期1431-1432,共2页Chinese Nursing Researsh

基　　金：2005年十堰市科技攻关项目(2005ZD013)。

摘　　要：[目的]探讨柔红霉素(DNR)血管外渗所致组织损伤早期最佳的处理方法。[方法]将12只家兔腿部制作成DNR外渗模型,每只兔4条腿分别应用不同方法处理。4条腿分为4组,即A组用云南白药乙醇膏,B组用海普林软膏,C组用湿润烧伤膏,D组用复方七叶皂苷钠凝胶,用药后7d采用空气栓塞将兔处死,进行局部组织病理学检查。[结果]C组局部组织病理学改变较轻。[结论]柔红霉素血管外渗所致组织损伤早期可采取湿润烧伤膏外敷。Objective： To probe into the optimal early handling method of tissue damage induced by daunorubicin vascular exosmosis. Methods： A total of 12 rabbits were made daunorubicin induced vascular exosmosis model. They were divided into 4 groups. Each limb of every rabbit was handled in different ways. Limbs of group A were applied Yunnanbaiyao plus alcohol cream. Limbs of group B were applied with Heparin ointment. Limbs of group C were handled with wetness burn cream. Limbs of group D were given compound aescin gel application. All rabbits were executed 7 days after the corresponding handling by aeroembolism. And locat tissue pathological changes of all rabbits were performed. Result： Limbs of group C had lighter local pathological changex Conclusion： Wetness burn cream may be applied to treat daunorubicin vascular exosmosis induced tissue injuries at early stage.

关 键 词：血管外渗 柔红霉素 云南白药 海普林 湿润烧伤膏 

分 类 号：R472[医药卫生—护理学]