热痹颗粒剂治疗类风湿关节炎湿热痹阻证临床疗效分析  

Clinical Therapeutic Effect Analysis of Pyretic Arthralgia Granules in Treating Rheumatoid Arthritis of Moist Heat Arthralgia Spasm Syndrome

作　　者：胡爱萍[1] 周武华[1] 

机构地区：[1]湖北中医学院,武汉430061

出　　处：《中华中医药杂志》2006年第5期277-279,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：湖北省科技厅科技攻关项目(编号:2003AA302B02)

摘　　要：目的:观察热痹颗粒剂治疗类风湿关节炎(RA)湿热痹阻证的临床疗效,为临证用药提供科学的依据。方法:将60例辨证属于湿热痹阻证的活动期RA患者,采用随机、阳性药平行对照的方法分组。实验组口服热痹颗粒剂每次2.0g,1日3次;对照组口服乐松,每次60mg,1日3次。两组疗程均为4周。结果:实验组与对照组均能改善主要症状,体征及理化指标,两组疾病疗效和中医证候疗效比较差异无显著性意义。结论:热痹颗粒剂能消肿、止痛、改善关节功能,且无明显毒副作用。Objective： To observe the clinical therapeutic effect of Pyretic Arthralgia granules in treating rheumatoid arthritis of moist heat arthralgia spasm syndrome, so as to provide scientific evidence in clinical Medication. Methods： Adopted random and positive parallel contrast methods, 60 cases of active stage rheumatoid arthritis （RA） patients whom were differentiated of symptoms and signs as moist heat arthralgia spasm syndrome were divided into groups. Experimental group took Pyretic Arthralgia granules 2. 0 g every time and 3 times a day orally; control group took Loxonin orally, 60 mg every time and 3 times a day. Both course of treatment in two sets were 4 weeks. Results： Experimental group and control group all could improve present symptoms, physical signs and physical - chemical index. There was not significance variance in two groups comparing the disease therapeutic effect with the therapeutic effect of syndrome of traditional Chinese medicine. Conclusion： Pyretic Arthralgia granules has the effects of detumescence, alleviating pain and improving Joint function, and has not obvious poison and side reaction. It is good for further generalizing and applying.

关 键 词：类风湿关节炎 湿热痹阻 热痹颗粒 临床观察 

分 类 号：R259[医药卫生—中西医结合]