水痘爆发病例的接种效率分析  

Analysis on Case-control Study of Varicella Outbreak

作　　者：梁飞琼[1] 何炳欣[1] 杨国[1] 郭志强[1] 

机构地区：[1]佛山市禅城区疾病预防控制中心,佛山528000

出　　处：《热带医学杂志》2006年第5期575-576,共2页Journal of Tropical Medicine

摘　　要：目的为了解佛山市水痘疫苗免疫效力(即疫苗保护效果),进而探讨水痘爆发的原因。方法选择2004年以来4起有代表性的水痘爆发,进行12∶配比的病例对照研究,共调查370例,并计算配比和不配比的水痘疫苗效力。结果病例组的水痘疫苗接种率显著低于对照组。配比后得出的水痘疫苗效力为84.4%。结论水痘疫苗效力<90%,仍偏低。水痘疫苗效力不够高和免疫接种率偏低是水痘爆发的主要原因。Objective To analysis the immunization efficacy of varicella vaccine, and find out the reasons for varicella outbreak in Foshan. Methods The 1：2 matching case-control studies was analyzed in 4 varicclla outbreak since 2004. The total number was 370 pairs. The vaccine efficacy was calculated with matching and without matching. Results The inoculation rate of case group was lower than the matching group. The vaccine efficacy was 84.4%. Conclusion The vaccine efficacy was low （〈90%）. The main reasons of the outbreak are that the vaccine efficacy was not high enough and the inoculation rate was low.

关 键 词：水痘 爆发 病例对照 疫苗效力 

分 类 号：R511.5[医药卫生—内科学]