芦荟抗肿瘤作用研究  

Experimental Studies on Anti-tumor Action of Aloe

作　　者：苏云明[1] 郭欣[1] 白云[1] 黄晓峰[1] 姜波[1] 白海玉[1] 

机构地区：[1]黑龙江中医药大学,哈尔滨150040

出　　处：《中国药师》2006年第6期486-488,共3页China Pharmacist

基　　金：黑龙江省科技攻关项目(编号:G99C19-9)

摘　　要：目的:探讨不同品种芦荟对荷瘤小鼠体内肿瘤的押制作用及木立芦荟对5-Fu的增效减毒作用。方法:观察不同品种及浓度的芦荟对S180荷瘤小鼠的抑瘤率、脾系数、体重和H22荷瘤小鼠生存时间的影响;并以脾系数为指标,观察木立芦荟对5-Fu的增效减毒作用。结果:不同品种及浓度的芦荟对S180荷瘤小鼠的肿瘤均具有不同程度的抑制作用,延长H22荷瘤小鼠生存时间。木立芦荟可显著改善5-Fu引起的机体生理机能紊乱,提高其抑瘤作用。结论:芦荟具有较好的抗肿瘤及增效减毒药理作用。Objective： To study anti-tumor function of various kinds of aloe in the mice. Method： The effects of various kinds of aloe on the effects of tumor-inhibited ,the spleen index,weigh of S180 tumor mice and life time of H22 bearing mice and efficacy enhancing and toxicity reducing of aloe arberescens miller on 5-Fu by the spleen index were observed. Result： Different kinds of aloe can inhibit S180 tumor and prolong the llfe time of H22 bearing mice. Aloe arberescens miller may improve the physical function disorder induced by 5-Fu, and anti-disease ability was developed. Conclusion： Aloe have better anti-tumor pharmacological action and efficacy enhancing and toxicity reducing.

关 键 词：芦荟 荷瘤小鼠 抗肿瘤 生命延长率 增效减毒 

分 类 号：R285.5[医药卫生—中药学]