消瘕方治疗乳腺癌术后110例的临床观察  

Clinical Observation of "Xiaojia Decoction" in Treating Postoperative Mammary Carcinoma in 110 Cases

作　　者：欧阳华强[1] 黄雯霞[1] 刘鲁明[1] 宋明志[1] 

机构地区：[1]复旦大学附属肿瘤医院中医科,上海200032

出　　处：《上海中医药杂志》2006年第6期50-51,共2页Shanghai Journal of Traditional Chinese Medicine

摘　　要：目的观察消瘕方预防乳腺癌术后的复发及转移。方法将110例乳腺癌术后患者分为中药组和对照组,两组均予以放疗、化疗及内分泌治疗,中药组术后及放化疗过程中即服中药消瘕方,对照组当疾病出现复发或转移时开始服用消瘕方。结果中药组74例中,复发4例,转移8例,死亡1例,此13例患者的中位无病生存期6.1年;对照组36例中的中位无病生存期3.6年,两者有显著性差异(P<0.05)。两组的10年无病生存率有极显著差异(P<0.01)。结论消瘕方能预防和延缓乳腺癌术后的复发及转移,提高患者的生活质量。Objective To observe the efficacy of ＂Xiaojia Decoction＂ in preventing the recurrence and metastasis of postoperative mammary carcinoma. Methods 110 subjects were randomly divided into two groups： treatment group and control group. All subjects were treated with radiotherapy, chemotherapy and endocrine therapy, and cases in the former group were integrated with oral decoction simultaneously. Results In the 74 patients in treatment group, 4 relapsed, 8 metastasized, and 1 patient died; the median disease free survival time（mDFS） for these 13 cases were 6.1 years. In the 36 cases in control group, the mDFS was 3.6 years, P〈 0.05; and the difference of 10 years mDFS was extremely significant（P〈 0.01 ）. Conclusion ＂Xiaojia Decoction＂ can prevent and delay the recurrence and metastasis of postoperative mammary carcinoma, along with an improvement in the quality of life.

关 键 词：消瘕方 乳腺癌 复发 转移 

分 类 号：R273[医药卫生—中西医结合]