健脾加味清毒方对儿童铅中毒的驱铅研究  

Clinical study of effects of traditional Chinese medicine on discharging Pb poisoning in children

作　　者：谭美珍[1] 林岚[1] 张春玲[1] 陈力[1] 彭静宜[1] 曾超宜[1] 陈咏冲[2] 

机构地区：[1]广州市儿童医院儿内科,广东广州510120 [2]中山医科大学附属第一医院,广东广州510080

出　　处：《中国儿童保健杂志》2006年第3期289-290,共2页Chinese Journal of Child Health Care

摘　　要：[目的]探讨中药驱铅对儿童血Pb及血Zn、Cu、Fe、Ca、Mn水平的影响。[方法]184例血铅≥0． 483μmol／L(100 μg／L)的患儿随机分为治疗组和对照组,治疗组服用健脾加味清毒方,对照组采用安慰治疗,观察30 d,检测驱铅前后两组患儿血Pb及血Zn、Cu、Fe、Ca、Mn水平。[结果]治疗组患儿服药后的血Pb明显低于服药前,血Zn 水平明显高于服药前,差异有显著性(P<0．01,0．05);与对照组比较,血Pb明显降低(P<0．01),血微量元素Fe、Cu、Ca、 Mn水平无明显差异(P>0．05)。[结论]中药对儿童早期铅中毒的驱铅效果好,不存在微量元素失衡。[Objective] To observe the effect of the content of Pb,Zn,Cu,Fe,Ca and Mn after the treatment by ira ditional Chinese medicine. [Methods] 184 children with blood lead level exceeding 0.1μg/ml were randomly divided into the treatment group and control group. The treatment group with traditional Chinese medicine, the control group with no drug,the observation period for both 30 days. [Results] The blood lead in treatment group was significantly lower than that of the chihtren cured by traditional Chinese medicine（P〈0.001 ）. the blood Zn increased（P〈0.05）; The blood lead in treatment group was significantly lower than in the control group（ P〈0.001 ） ,while the content of Cu,Fe,Ca ,Mn remained stahle（P〉0.05）. [Conclusion] Traditional Chinese medicine was effective in curing children with Pb poisoning.which would not cause trace elements inbalance.

关 键 词：铅中毒 中药 微量元素 儿童 

分 类 号：R722[医药卫生—儿科]