黏附分子与心肺转流术肺损伤  

Adhesion molecules and cardiopulmonary bypass-induced lung injury

作　　者：杨维君[1] 张泽伟[1] 

机构地区：[1]浙江大学医学院附属儿童医院心胸外科,杭州市310003

出　　处：《国际麻醉学与复苏杂志》2006年第3期167-169,共3页International Journal of Anesthesiology and Resuscitation

基　　金：浙江省科技厅重点课题项目(项目编号2004c23016)

摘　　要：Cardiopulmonary bypass (CPB)-induced lung injury is the most important complication in open cardiac procedures, which affects surgical prognosis directly. During the inflammatory response, interaction between activated leukocytes and endothelial cells is mediated through the expression of three main groups of adhesion molecules: the selectins, the integrins, and the immunoglobulin superfamily. The preventive effect of anti-adhesion on CPB-induced lung injury is supposed to be the farget for farther research.Cardiopulmonary bypass （CPB）-induced lung injury is the most important complication in open cardiac procedures, which affects surgical prognsis directly. During the inflammatory response, interaction between activated leukocytes and endothelial cells is mediated through the expression of three main groups of adhesion molecules： the selectins, the integrins, and the immunoglobulin superfamily, The preventive effect of anti-adhesion on CPB-induced lung injury is supposed to be the farget for farther research.

关 键 词：cardiopulmonary bypass LUNG adhesion molecules 

分 类 号：R654.1[医药卫生—外科学]