流动注射后化学发光法测定舒必利  

Determination of sulpiride based on flow injection post-chemiluminescence

作　　者：孙述文[1] 吕九如[1] 

机构地区：[1]陕西师范大学化学材料科学学院,陕西西安710062

出　　处：《陕西师范大学学报（自然科学版）》2006年第2期80-83,共4页Journal of Shaanxi Normal University：Natural Science Edition

基　　金：国家自然科学基金资助项目(20275023);陕西省自然科学基础研究计划项目(2002B12)

摘　　要：当舒必利溶液注入到铈（Ⅳ）-亚硫酸钠化学发光反应体系中后，立即产生一个更强的后化学发光反应．据此建立了利用后化学发光反应测定舒必利的流动注射化学发光新方法，并对其后化学发光反应的动力学性质、化学发光光谱、荧光光谱进行了研究，讨论了可能的反应机理．结果表明，所建方法的检出限为3×10^8g／mL舒必利，相对标准偏差为1．6％（c=1．0×10^-6g／mL舒必利，n=11），线性范围为1．0×10^-7～1．0×10^-5g／mL（r=0．9991）．A stronger post-chemiluminescence （PCL） reaction was observed when sulpiride was injected into the mixture of Ce （Ⅳ）-sodium sulfite chemiluminescence （CL） reaction system. According to this, a new flow injection CL method for determination of sulpiride was established. A possible mechanism for the PCL reaction was discussed via the studies of kinetic characteristics, the CL spectra, the UV absorption spectra and the fluorescence spectra. The relative standard deviation （RSD） for determination of sulpiride was 1.6% （n = 11, c= 1.0 × 10^-6g/mL）. The PCL intensity responded linearly to the concentration of sulpiride in the range 1.0 × 10^-7～1.0 × 10^-5g/mL with a linear correlation of 0. 9991. The detection limit was 3 × 10^-8g/mL. The method had been applied to determination of sulpiride in the tablets.

关 键 词：后化学发光 铈(Ⅳ) 亚硫酸钠 舒必利 

分 类 号：O657.3[理学—分析化学]