脂联素与冠心病关系的研究进展  

Advances on the Relationship between Adiponectin and Coronary Heart Disease

作　　者：王丽洁[1] 罗心平[1] 施海明[1] 

机构地区：[1]上海复旦大学华山医院心内科,上海200040

出　　处：《医学综述》2006年第11期682-684,共3页Medical Recapitulate

摘　　要：脂联素是一种主要由脂肪组织分泌的细胞因子,早在1995年就为人们所发现。但直到2001年,人们才开始注意到它具有调节糖脂代谢、抗糖尿病、抗动脉粥样硬化、抗炎症等诸多特性。随后,由于血中脂联素浓度的大规模检测得以实现,许多关于脂联素的临床研究结果陆续发表,使得其在代谢综合征和心血管疾病中的重要作用得以证实。本文仅就脂连素在冠心病研究领域取得的最新进展简要综述。Adiponectin, founded earlier in 1995, is a kind of cell factor which mainly secreted by adipose tissue. But until 2001 ,we haven＇t noticed its multiple characters and functions in regulation of glucolipid metabolism, anfidiabetic, antiatherosclerofic and antiinflammatery. Later, thanks to the fulfillment of detection of blood adiponectin concentration in large scale, many clinical research results came out, which verified the adiponectin＇s significant role in metabolic syndrome and cardiovascular disease. In this review, we only focus on the recent progress in the link of adiponectin to coronary heart disease.

关 键 词：冠心病 急性冠脉综合征 脂联素 

分 类 号：R541.4[医药卫生—心血管疾病] R543.5[医药卫生—内科学]