One Pot Reduction of Imines Generated in-situ from Aldehydes and Amines by the NaBH4-InCl3 System  

作　　者：RAVI, Varala RAMU, Enugala VIJAY KUMAR, Ponnamaneni SRINIVAS RAO, Adapa 

机构地区：[1]Indian Institute of Chemical Technology, Hyderabad-500 007, India

出　　处：《Chinese Journal of Chemistry》2006年第6期807-810,共4页中国化学（英文版）

摘　　要：A combination of sodium borohydride and a catalytic amount of indium（Ⅲ） chloride in acetonitrile reduces imines formed in-situ from aldehydes and amines to the corresponding functionalised secondary and tertiary amines in moderate to good yields. Noteworthy is that highly chemoselective reactions were achieved in the presence of other functional groups such as halogens, carbon-carbon double bonds and hydroxyl groups.A combination of sodium borohydride and a catalytic amount of indium（Ⅲ） chloride in acetonitrile reduces imines formed in-situ from aldehydes and amines to the corresponding functionalised secondary and tertiary amines in moderate to good yields. Noteworthy is that highly chemoselective reactions were achieved in the presence of other functional groups such as halogens, carbon-carbon double bonds and hydroxyl groups.

关 键 词：NaBH4-InCl3 ALDEHYDE amine One Pot Reduction 

分 类 号：O623.511[理学—有机化学]