Reduction of Azide to Amine Using Fe/AlCl3 or Fe/BiCl3 System in Aqueous EtOH  

作　　者：郑鹏武 段学民 王伟 王晓季 郭玉萍 涂其冬 

机构地区：[1]School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang, Jiangxi 330013, China [2]School of Chemical Engineering, Anshan University of Science and Technology, Anshan, Liaoning 114044, China

出　　处：《Chinese Journal of Chemistry》2006年第6期825-826,共2页中国化学（英文版）

摘　　要：Azides were reduced to the corresponding amines by two new metal/Lewis acid systems in aqueous EtOH with yields ranging from 80% to 95%. The new reduction systems were Fe/AlCl3·6H2O or Fe/BiCl3 system in H2O/ethanol （2 ： 1, Ⅴ ：Ⅴ） at room temperature. Fifteen azides with different functional groups were well reduced to the corresponding amines in excellent yields.Azides were reduced to the corresponding amines by two new metal/Lewis acid systems in aqueous EtOH with yields ranging from 80% to 95%. The new reduction systems were Fe/AlCl3·6H2O or Fe/BiCl3 system in H2O/ethanol （2 ： 1, Ⅴ ：Ⅴ） at room temperature. Fifteen azides with different functional groups were well reduced to the corresponding amines in excellent yields.

关 键 词：AZIDE REDUCTION AMINE AMIDE 

分 类 号：O613.61[理学—无机化学]