抗生素相关性腹泻的临床研究  

Clinical observation and prevention of antibiotic associated diarrhea

作　　者：陈建荣[1] 郭锡明[1] 

机构地区：[1]南通大学附属医院分院消化内科,226001

出　　处：《中国医师进修杂志（内科版）》2006年第6期17-18,共2页Chinese Journal of Postgraduates of Medicine

摘　　要：目的了解医院抗生素相关性腹泻(AAD)的临床特点、发病率、发病因素,提出预防控制措施。方法对合并AAD患者的临床资料进行回顾性分析。结果AAD的发生率为9.3%,与使用抗生素种类、联合用药数量及疗程、采用医疗干预措施、年龄等因素有关。引起AAD的抗生素依次为广谱青霉素或加酶抑制剂、第三代头孢菌素类、青霉素类、克林霉素、碳青酶烯类、头孢二代、喹诺酮类。结论合理使用抗生素、控制广谱抗生素的应用、减少侵袭性操作是预防控制医院感染AAD的关键措施。Objective To investigate the characteristics,the ineidenee, relative factors of antibiotie associated diarrhea （AAD）, and prevent and control it. Methods Retrospective analysis was performed in 78 patients with AAD. Results Prevalence ratio of AAD was 9.3 %, the risk of AAD related to the kinds of using mix antibiotics and period of treatment, using many meddle measures for medical and age. The antibiotics causing AAD were extending penieillin or third cephalosporins, penicillin, carbapenemases, second cephalosporins. Conclusions Rational use of antibiotic, control use of antibiotic and reduce the state of consciousness are the key measures to prevent and control the AAD.

关 键 词：腹泻 抗生素 预防控制 

分 类 号：R442.2[医药卫生—诊断学] R978.11[医药卫生—临床医学]