原发性高血压患者动脉硬化指数和C-反应蛋白的性别差异  

SEX DIFFERENCES IN ARTERIAL STIFFNESS INDEX AND C-REACTIVE PROTEIN IN PATIENTS WITH ESSENTIAL HYPERTENSION

作　　者：张明华[1] 刘国树[1] 覃秀川[1] 刘蓉[2] 

机构地区：[1]解放军总医院南楼二科,北京100853 [2]解放军总医院门诊内科,北京100853

出　　处：《实用临床医药杂志》2006年第3期38-40,共3页Journal of Clinical Medicine in Practice

摘　　要：目的探讨原发性高血压患者的动脉硬化指数和炎性因子C-反应蛋白是否存在性别差异及其意义。方法对本院门诊汉族原发性高血压患者90例(男性45例,女性45例)进行动脉硬化指数(ASI)、C-反应蛋白(CRP),以及血尿酸、血糖、血脂、肌酐、尿素氮等血液生化指标及一般情况检测,并进行对比分析。结果①汉族女性高血压患者的动脉硬化指数、C-反应蛋白高于男性患者(P<0.05),HDL-C水平亦显著高于男性患者(P<0.001);②男性患者的血肌酐、尿酸水平显著高于女性患者(P<0.001)。结论我国汉族原发性高血压患者的临床特征存在着性别差异。Objective To investigate sex differences in arterial stiffness index and c-reactive protein in patients with essential hypertension. Methods 90 Han ethnic patients with essential hypertension were examined, 45 of whom were male, and the rest female. The demographic characteristics, arterial stiffness index, c-reactive protein and blood biochemical parameters were measured and compared between the male patients and female patients. Results Higher values of arterial stiffness index and c-reactive protein （both P〈0.05） and higher values of HDL-C （P〈0. 001） in the female hypertensive patients were observed. The values of blood creatinine and uric acid in the male patients were statistically higher than those of the female patients （both P 〈 0. 001）. Conclu- sion There are sex differences in arterial stiffness index, c-reactive protein, HDL-C, uric acid and creatinine between male and female Han ethnic patients with essential hypertension.

关 键 词：原发性高血压 动脉硬化指数 C-反应蛋白 性别 

分 类 号：R544.1[医药卫生—心血管疾病]